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cuff1silver and carnelianbracelet cuffcuff 1  (kŭf)n.1. a. A fold used as trimming at the bottom of a sleeve.b. A band, often having an opening with a button closure, at the bottom of a sleeve.2. The turned-up fold at the bottom of a trouser leg.3. The band at the top of a sock.4. The part of a glove that extends over the wrist.5. A bracelet consisting of a curved, open-ended band, as of metal or resin, that fits the wrist firmly without a clasp.6. A handcuff.7. Medicine An inflatable band, usually wrapped around the upper arm, that is used along with a sphygmomanometer in measuring arterial blood pressure.tr.v. cuffed, cuff·ing, cuffs 1. To form a cuff or cuffs on.2. To put handcuffs on.Idioms: off the cuff In an extemporaneous or informal manner. on the cuff On credit.[Middle English cuffe, mitten.]cuff 2  (kŭf)tr.v. cuffed, cuff·ing, cuffs To strike with or as if with the open hand; slap.n. A blow or slap with the open hand.[Origin unknown.]